BPC-157 + TB-500 + GHK-Cu

BPC-157 + TB-500 + GHK-Cu Peptide Blend (Research Use Only)

Intended Use:
This product is a research-only peptide blend containing BPC-157, TB-500, and GHK-Cu. It is supplied exclusively for laboratory investigation, including in vitro and approved in vivo animal studies.
Not for human consumption, medical, or veterinary use.

Product Overview

The blend consolidates three mechanistically distinct peptides into a single formulation to facilitate:

• Studies on tissue repair and remodeling
• Investigation of inflammatory and immune signaling pathways
• Research on oxidative stress and age-associated changes
• Exploration of antimicrobial and barrier-supportive properties during healing

By combining these components, the product simplifies research workflows that would otherwise require managing three separate peptide vials.

Component Summary

BPC-157

• Synthetic pentadecapeptide modeled on a gastric protection factor
• Documented in animal studies to:
• Influence nitric oxide signaling (iNOS/eNOS)
• Modulate VEGF and related angiogenic pathways
• Adjust cytokine profiles in inflammatory models
• Commonly investigated in:
• Gastrointestinal injury
• Tendon, ligament, and muscle damage
• Neurovascular and CNS injury paradigms

TB-500

• Synthetic peptide derived from thymosin beta-4
• Known for:
• Binding to actin to regulate cell movement and division
• Affecting transcriptional control of:
• NF-κB and TLR pathways
• PI3K/Akt/eNOS, Notch, TGF-β, Ang-1/Tie2, and Wnt signaling
• Utilized to study:
• Wound closure kinetics
• Vascularization and fibrosis control

GHK-Cu

• Naturally occurring GHK tripeptide chelated with Cu²⁺
• Reported actions include:
• Activation of metalloproteinases and anti-protease systems
• Enhanced collagen and extracellular matrix synthesis
• Increased superoxide dismutase (SOD) and glutathione production
• Support of copper-dependent enzymes involved in collagen cross-linking
• Frequently used in:
• Skin and wound healing models
• Studies of oxidative stress and tissue aging

Rationale for Combined Use

The blend is formulated to enable investigation of converging biological pathways:

• Inflammation Regulation
• NO and cytokine modulation (BPC-157)
• Transcriptional control of inflammatory mediators (TB-500)
• Antioxidant-driven dampening of inflammatory cascades (GHK-Cu)
• Tissue Repair and Remodeling
• Cell recruitment and proliferation (TB-500)
• Growth factor and microvascular support (BPC-157)
• ECM clearance and reconstruction (GHK-Cu)
• Antimicrobial and Oxidative Stress
• Peptide- and copper-associated antimicrobial activity (BPC-157, GHK-Cu)
• Reinforcement of endogenous antioxidant systems (GHK-Cu)

Applications

Suitable for research projects exploring:

• Multi-agent vs. single-agent regenerative peptide protocols
• Interactions between NO signaling, actin dynamics, and copper-mediated enzymes
• Changes in healing efficiency and quality under inflammatory or oxidative stress conditions
• Mechanistic contributors to age-related decline in tissue repair